Subject: Re: Cognitive decline
My wife has no real interest or skills wrt investing. I may start with an inquiry to my CFP and/or estate planning attorney for their thoughts as well.

Write up instructions for her to move the money from individual stocks & bonds to Vanguard LifeStrategy Moderate Growth Fund (VSMGX). In taxable accounts, gradually to avoid large capital gains tax. In IRAs, just do it ASAP.
Also instructions for her to set up an Automatic Withdrawal Plan, and say what the automatic amount should be.