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Trump will have vast difficulty in getting his nominees confirmed in the new Congress.
Bush didn't have a problem seating people: wait until Congress goes on recess, then appoint by decree.
Of course, if Trump the Magnificent does not have that much patience, he can appoint "acting" officials.
From the net sifter, re 2020:
In 2020, several key departments and agency-level roles within the Donald Trump administration were led by unconfirmed, acting officials rather than Senate-confirmed appointees
According to official archives and tracking data from Ballotpedia and the Trump White House Archives, prominent high-level and cabinet positions operating under acting leadership in 2020 included:
Acting Attorney General: Jeffrey Rosen (following the departure of William Barr in December 2020)
Acting Secretary of Defense: Christopher C. Miller (appointed in November 2020 following the removal of Mark Esper)
Acting Secretary of Homeland Security: Chad Wolf / Peter Gaynor (with Chad Wolf serving as Acting DHS Secretary through much of 2020)
Acting White House Chief of Staff: Mick Mulvaney (who served as acting chief of staff until March 2020)
Broader tracking data compiled by the Partnership for Public Service notes that across roughly 800 tracked key Senate-confirmed federal positions during the administration, dozens of major and sub-cabinet posts at any given time relied on temporary holdovers, unconfirmed acting officials, or vacant nominations.
Taking a line from Bush 43, Trump doesn't need a "permission slip" to fill his clown car.
Steve