Tell me, when was the most significant spike in synthetic opioid deaths?

HINT: DURING THE TRUMP ADMINISTRATION.

The grafts in your link all stop at the year 2021.

'Biden's open borders fuel America's deadly fentanyl crisis'
September 21, 2022
Snip
' While our brave border patrol agents are doing everything they can to stop the flow of these deadly drugs into America's neighborhoods, the Biden administration has left them understaffed and under-resourced. I've heard about it during my trips to the border. But the fentanyl crisis isn't only a problem in border states like Arizona. It's killing Floridians too. More than 2,000 Floridians have died in 2022 from opioid overdoses.

What is President Biden doing to stop the fentanyl killing spree? Nothing.'

rickscott.senate.gov - Biden s open borders fuel america s deadly fentanyl crisis

'Democrats, Republicans, alike, criticize Biden border policy'
Snip
"The Biden open borders agenda has created a humanitarian crisis that is increasing crime and violence in our streets, overwhelming local communities, and worsening the opioid crisis," Paxton said in a written statement.'

cbsaustin.com - Democrats republicans alike criticize biden border policy texas mexico immigration title migrants austin

'Portman: Biden's border policies are worsening the opioid crisis'
Snip
'This six-month total is more than all of last year, and CBP believes the vast majority of drugs are getting in without being stopped.

The reason for this is clear ' the Biden administration's radical policy changes have encouraged the drug cartels to smuggle more unlawful migrants and lethal, illicit substances across our southern border.

The Biden administration systematically dismantled the existing border security framework put in place by the Trump administration, including revoking the COVID-19 emergency declaration for the border, stopping construction of the border fence, suspending the Remain in Mexico policy, canceling Asylum Cooperative Agreements and severely reducing immigration enforcement within the United States.'

knoxpages.com - Portman bidens border policies are worsening the opioid crisis

Plenty more info if you care to look up Biden's drug worsening policies.