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Author: PucksFool 🐝  😊 😞
Number: of 48466 
Subject: As we age into our 40s and beyond ...
Date: 04/13/2025 2:13 PM
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... maybe p-Tau 217 screening should be part of a routine physical.

https://erictopol.substack.com/p/the-breakthrough-...
Since that discovery of a blood biomarker for Alzheimer’s disease, there has been remarkable further advances, including the availability of the test over the past year at a cost of approximately $200. In this edition of Ground Truths, I’ll go through the key questions as follows:

1 What is p-Tau217 measuring?
- How does it compare with other phosphorylated Tau proteins, CSF and PET scans?
2 How can we predict AD over 20 years in advance?
3 What can be done to lower p-Tau 217?
4 Where is this field headed?
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Author: onepoorguy 🐝  😊 😞
Number: of 48466 
Subject: Re: As we age into our 40s and beyond ...
Date: 04/13/2025 2:18 PM
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So the question is: would you want to know given there are no treatments available? I'm not sure I would, at least not yet. I already know I have a family history (mom). If I was maybe 70(?), I might want to know. But at age 40 or 50? Not sure.
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Author: PucksFool 🐝  😊 😞
Number: of 48466 
Subject: Re: As we age into our 40s and beyond ...
Date: 04/13/2025 3:53 PM
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According to the linked article there are dietary and life style changes that can reduce the proteins that seem to be most responsible for non-genetic Alzheimers.
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